Phlebolymphedema is a unique condition of combined insufficiency of both the venous and lymphatic systems. There is a very close relation between the venous and lymphatic systems; therefore a venous obstruction may develop a phlebo-lymphedema. Here we find a failure in the dual outflow system, and although being totally different hemodynamic mechanisms, they are mutually dependant and complementary circulation systems. Due to their intimately integrated function, failure in one system means then additional burden and overload of the other.
There are various causes: Primary Phlebolymphedema and Secondary Phlebolymphedema
Primary Phlebolymphedema is caused by a congenital defect, involving an outset of diffused trancular lymphatic malformation, affecting both the venous and lymphatic systems. Primary Phlebolymphedema is still a retativelly unknown condition and in the majority of cases represents the clinical manifestation of Klippel –Trenaunay Syndrome. The presence of an arteriovenous malformation makes the overall condition of Primary Phlebolymphedema much harder to manage. It is also thought that Long-term strain on the lymphatic system can be a cause of phlebo-lymphedema
Secondary Phlebolymphedema is an acquired condition that starts off with chronic Venus insufficiency due to various causes, and which latter leads to chronic lymphatic insufficiency. In the presence of venous hypertension, which is characteristic of most venous disorders, the increase in lymphatic flow becomes much greater than the lymph transport capacity. Treatment for chronic Secondary Phlebolymphedema, consists of treating the venous abnormality, and watching regression of the lymphatic problem.
The diagnosis of Primary and Secondary Phlebolymphedema is based on a detailed history and physical examination, and related tests.
Information source and references:
Dermatologic complications:
No hay comentarios :
Publicar un comentario